Development and Evaluation of Ketoprofen Acrylic Transdermal Patches
نویسندگان
چکیده
منابع مشابه
Development and evaluation of carvedilol transdermal patches.
Transdermal patches of carvedilol with a HPMC-drug reservoir were prepared by the solvent evaporation technique. In this investigation, the membranes of Eudragit RL100 and Eudragit RS100 were cast to achieve controlled release of the drug. The prepared patches possessed satisfactory physicochemical characteristics. Thickness, mass and drug content were uniform in prepared batches. Moisture vapo...
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Objective: Azelnidipine, a long-acting dihydropyridine based calcium channel blocker, on oral administration, the drug undergoes extensive first pass metabolism. Delivery of azelnidipine (AZP) via transdermal route would minimize some of the deficiencies associated with the oral delivery and increase the bioavailability of the drug. In the present study, is to investigate the development and ev...
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Most of the therapeutic agents are recommended through an oral route, but oral route has disadvantages like first pass metabolism, liver toxicity, etc, due to gastrointestinal pH. This leads poor bioavailability of drugs, which are not stable in G.I pH. To overcome this problem, increase the bioiavailibility, reduce the dose and dose dumping Transdermal delivery system is better option as novel...
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Transdermal patches are now widely used as cosmetic, topical and transdermal delivery systems. These patches represent a key outcome from the growth in skin science, technology and expertise developed through trial and error, clinical observation and evidence-based studies that date back to the first existing human records. This review begins with the earliest topical therapies and traces topic...
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Drug Delivery through skin would provide a useful alternative to oral delivery, which has numerous side effects. Therefore, the present investigation was aimed to develop sustained release transdermal therapeutics system containing Glipizide with varying ratios of HPMC & PVPK30 using solvent evaporation technique. Ten different formulations were prepared keeping the concentration of Glipizide c...
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ژورنال
عنوان ژورنال: Tropical Journal of Pharmaceutical Research
سال: 2012
ISSN: 1596-9827,1596-5996
DOI: 10.4314/tjpr.v11i4.5